Every so often I try new mods, and occasionally they change how I want to run my career. Sometimes, I find a few mods at the same time, and it makes sense to start a new career. So it goes with Quest 3.
The biggest change with Quest IV is switching to Historical Progress Tech Tree. It has a more realistic feel and lends itself better to my playing style, and plays better with Cryogenic Tanks than CTT.
Another change will be adopting SmartParts for controlling staging during launch. This allows my kOS launch program to focus solely on guidance, while allowing better custom staging for rockets.
Finally, I will not be using stock 1.25/2.5/3.75m engines or tanks, relying solely on KWRocketry, Cryogenic Engines, and Kerbal Atomics (if I make it that far!).
The early emphasis will be on an uncrewed flyby to Duna during the first transfer window, and establishing long-term stations around Mun and Minmus.
Finally, a list of mods.